EVENTS
Wednesday, July 2nd, 2025, 10am CT
Zoom Community Meeting
The use of Kaandoosh as a Biodegradable Disinfectant and Anticancer Agent by Johanna Bernu
This presentation is on The use of Kaandoosh as a Biodegradable Disinfectant and Anticancer Agent and is presented by Johanna Bernu, student researcher and rising Yale freshman.
Commonly known as the yellow water lily root or kaandoosh in Ojibwe language, the rhizome of Nuphar advena is utilized by Indigenous communities for treating a wide variety of ailments, including bacterial overgrowth and gastrointestinal issues. Prior research supported these usages: showing Nuphar advena’s effectiveness against bacterial overgrowths without hazardous effects on water systems, yet questions remained on heavy metal interactions' affect on human health. This study aims to investigate the impact of Nuphar advena rhizome on cancer cells (67NR, 4T1, MDA-ME-231, MiaPaCa-2) while emphasizing Ojibwe teachings around efficacy. Rhizome extractions were made with acidic, basic, and neutral water, acetone, ether, ethanol, ethyl acetate, and chloroform. The MTT assay produced EC50 values revealing that ether extractions were effective against all cancer cell lines in concentrations less than 500 mg/L. These results contribute to the ethnopharmacological knowledge and reappraisal of Ojibwe medicinal teachings.
Pollution from high sulfide mines can affect the growth of native plants jeopardizing the positive benefits of these resources.
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